Shwayta Kukreti MD, PhD, Presenter: Nothing to Disclose

Albert Cerussi PhD, Abstract Co-Author: Nothing to Disclose

Bruce Tromberg MD, Abstract Co-Author: Nothing to Disclose

Enrico Gratton PhD, Abstract Co-Author: Nothing to Disclose

The purpose of this exhibit is to 1. Review the principles of how light photons interact with matter. 2. Review the Tissue Optical Index: the physics basis for this index, and its application for breast cancer imaging. 3. Review the Self Referencing Differential Spectroscopic Method: the mathematics, and application for breast cancer imaging.  

1. Review the fundamentals of the spectroscopy: the attenuation of light through matter, including the fundamental physics and chemistry principles 2. Review the Tissue Optical Index -Review the mathematical methods to derive this index towards a way to demonstrate changes in tissue state non-invasively -Explain the clinical interpretation of the index value -Review the clinical utility for breast imaging 3. Review the Self Referencing Differential Spectroscopic Analysis Method -Review the mathematics of this method towards the identification of a “cancer signature” spectrum -Explain the biochemical basis of the spectrum -Review the clinical utility for breast imaging 4. Summary 5. Future directions of tissue spectroscopy  

http://abstract.rsna.org/uploads/2014/14009848/14009848_qcxs.pdf

Kukreti, S, Cerussi, A, Tromberg, B, Gratton, E, Molecular Biophysics: The Interaction of Light and Matter-Spectroscopic Methods in Breast Imaging.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14009848.html