David Michael Valenzuela MD, Presenter: Nothing to Disclose

Sara Katherine Plett MD, Abstract Co-Author: Nothing to Disclose

Sandeep Singh Arora MBBS, Abstract Co-Author: Nothing to Disclose

Spencer Caton Behr MD, Abstract Co-Author: Research Grant, General Electric Company

1. Discuss the contemporary classification of the histiocytoses. 2. Review the imaging characteristics of common histiocytoses with an emphasis on extra-osseous manifestations. 3. Assist in formulating an appropriate differential diagnosis of hystiocytoses relevant to radiology with multiple cross-sectional imaging examples.

Contemporary pathologic classification of the histiocytoses Practical radiographic classification of common histiocytoses Review of imaging findings of common histiocytoses Sample cases (CT and MRI) Histiocytic disorders have historically presented a diagnostic challenge.  A number of histiocytoses have been described, but the radiologist may only encounter a few given their rarity.  Familiarity with the imaging appearance of the more common entities such as Langerhans cell histiocytosis, Erdheim-Chester disease, Rosai-Dorfman, and juevile xanthogranuloma will assist with formulating an appropriate differential diagnosis. We will present a concise schema depicting the currently accepted histopathological classification with an emphasis on the relevant distinguishing imaging characteristics. Cross-sectional images of the extra-osseous manifestations of Langerhans cell histiocytosis, Erdheim-Chester disease, juvenile xanthogranuloma and Rosai-Dorfman disease will be included.

http://abstract.rsna.org/uploads/2014/14009788/14009788_g2kf.pdf

Valenzuela, D, Plett, S, Arora, S, Behr, S, Histiocytosis for the Radiologist: Extra-osseous Manifestations and Distinguishing Features or a Rare Group of Disorders.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14009788.html