Siddaroodha Mahantappa Sajjan MBBS, Presenter: Nothing to Disclose

Zarina Abdul Assis MBBS, MD, Abstract Co-Author: Nothing to Disclose

Sunitha P Kumaran MBBS, MD, Abstract Co-Author: Nothing to Disclose

Sanjaya Viswamitra MD, Abstract Co-Author: Nothing to Disclose

• To educate the reader about embryological development of brain and MRI findings of congenital malformations of the brain. •To understand the correlation between the stage of development and resultant malformation

• Introduction: Congenital anomalies of the brain are extremely complex and are best studied by correlating with embryological development. • Methods: 91 patients scanned between 2008 to 2013 on 1.5T MRI who had congenital malformations of the brain (other than neuro cutaneous syndromes) are presented under the following subheadings based on the stage of developmental defect: 1) Defective dorsal induction (3 – 4 weeks): Chiari I, II and III malformations, cephaloceles. 2) Defective ventral induction (2 – 3 months): Corpus callosum agenesis/dysgenesis, holoprosencephaly, septo optic dysplasia, complete commissural agenesis, Joubert’s syndrome, Dandy Walker complex and cerebellar hypoplasia/dysplasia. 3) Defective cellular migration (3 – 5 months): Agyria--pachygyria complex, heterotopia, polymicrogyria, schizencephaly, Lhermitte - Duclos disease, coronal cleft in the pons.  

http://abstract.rsna.org/uploads/2014/14009496/14009496_ai92.pdf

Sajjan, S, Assis, Z, Kumaran, S, Viswamitra, S, Chronology in Embryology: Review of the Timeline of the Congenital Malformations of Brain.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14009496.html