Wang Mingyue, Presenter: Nothing to Disclose

Jianbo Gao MD, Abstract Co-Author: Nothing to Disclose

Zhou Yue, Abstract Co-Author: Nothing to Disclose

To assess the image quality and detection between Spectral CT with low-osmolar contrast and conventional CT with conventional contrast.

Forty-eight rabbits with VX2 liver tumors were randomly divided into A group and B group. On the 7th day after implantation, the rabbits in group A underwent conventional CT enhancement scan with conventional contrast (Ioversol 320mgI/ml) and the rabbits in group B underwent spectral CT with low-osmolar contrast (Iopromide 270mgI/ml). The tumor-to-liver contrast-to-noise ratio (CNR) were calculated in group A in arterial phase, while The CNR were calculated at the optimal CNR keV in group B in arterial phase. The lesion conspicuity scores (LCS) and overall image quality scores (OQS) in the two groups were recorded.

The CNR of the group B had no significant difference from that of the group A (1.73±2.52vs1.99±1.73，p=0.092). The LCS and OQS of the group B had no significant difference from that of group A (3.500±0.608 vs 3.604±0.675 p= 0.577; 3.563±0.496 vs3.354±0.561 p= 0.179)

Spectral CT associated with low-osmolar contrast can greatly reduce contrast media dose without compromising image quality and detection.

reduce contrast media dose without compromising image quality and detection

Mingyue, W, Gao, J, Yue, Z, Spectral CT with Low-osmolar Contrast in VX2 Liver Tumor: Investigation of Image Quality and Detection.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14009365.html