Hao Tang, Presenter: Nothing to Disclose

Zi Wang, Abstract Co-Author: Nothing to Disclose

Xiaoyan Meng MD, Abstract Co-Author: Nothing to Disclose

To evaluate ability to depict anatomy and complications of renal vascular transplant with unenhanced magnetic resonance (MR) angiography with spatial labeling with multiple inversion pulses (SLEEK), and to compare the results with color Doppler (CD) ultrasonography (US), digital subtraction angiography (DSA), and intraoperative findings.

This study was approved by the institutional review board and written informed consent was received before examination. Seventy-five patients who underwent renal transplant were examined with unenhanced MR angiography with SLEEK and CD US. DSA was performed in 15 patients. Surgery was performed in eight patients. The ability of SLEEK to show transplant renal vascular anatomy and complications was evaluated by two experienced radiologists who compared the results with CD US, DSA, and intraoperative findings. 

Patients successfully underwent SLEEK MR angiography. Transplant renal vascular anatomy was assessed in 87 arteries and 78 veins. Twenty-three patients were diagnosed with renal vascular complications from transplantation, which included 14 with arterial stenosis, three with arterial kinking, two with arteriovenous fistulas, two with venous stenosis, one with pseudoaneurysms, and one with fibromuscular dysplasia. Three patients had two renal transplants and nine patients had nine accessory renal arteries. More accessory renal arteries were detected with SLEEK than with CD US. Correlation was excellent between the stenosis degree with SLEEK and DSA (r= 0.96; P ＜.05). Bland-Altman plot showed overestimation stenosis degree (mean bias, 3.2%±7.3% [standard deviation]). For those with significant artery stenosis (.50% narrowing) proved by DSA (n= 7) or via surgery (n= 3), positive predictive value was 91% (10 of 11) .

Unenhanced MR angiography with SLEEK preliminarily proved to be a reliable diagnostic method for depiction of anatomy and complications of renal vascular transplant. It may be used for evaluation of patients with renal transplantation, and in particular for those with renal insufficiency.

Unenhanced MR angiography by using SLEEK may be a reliable diagnostic method for depiction of transplant renal vascular anatomy and complications; furthermore, it does not carry the risk of nephrogenic systemic fibrosis and contrast-induced nephropathy in patients with renal insufficiency.

Tang, H, Wang, Z, Meng, X, Depiction of Transplant Renal Vascular Anatomy and Complications: Un-enhanced MR Angiography by Using Spatial Labeling with Multiple Inversion Pulses.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14009337.html