Jehan Al-Rayahi MD, Presenter: Nothing to Disclose

Walid Mabrouk Mubarak, Abstract Co-Author: Nothing to Disclose

Khaled Salem Doghem, Abstract Co-Author: Nothing to Disclose

To understand the anatomy & distinctive features of deep grey matter . The basal ganglia & thalami (BG &T)constitute paired structures of the deep grey matter nuclei that are unique in their high metabolic activity, rich blood supply and mitochondrial content. This makes them susceptible to a wide spectrum of metabolic, toxic and vascular pathology. To present an overview of the different etiologies of BG&T abnormalities. These include: 1)Toxic, 2)Metabolic, 3)Vascular, 4)Infectious/Inflammation & 5)Heredeitary/Degenrative To learn the approach in the assessment of abnormalities of the BG&T which include the 3 steps: 1) Is it an isolated abnormality of the basal galnglia? If not, what other regions are involved? 2) what is the primary nuclei affected? & 3) what MRI signal changes is noted? To understand that findings should always be interpreted with attention to patient age, clinical setting (including acuity/chronicity of the presentation) & correlation with laboratory findings

1. Introduction (Differentiating Features & Diagnostic Approach) 2. Anatomy of the Basal Ganglia 3. Table: Causes of Basal Ganglia abnormalities on MRI 4. Illustrative examples from each group of etiology: a. Metabolic b. Toxic c. Vascular d. Infection/Inflammation e. Inherited/Neurodegenrative 5. Conclusion

http://abstract.rsna.org/uploads/2014/14009027/14009027_xd4d.pdf

Al-Rayahi, J, Mubarak, W, Salem Doghem, K, Abnormalities of the Basal Ganglia and Thalamus; MRI Findings in Common and Uncommon Entities.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14009027.html