Guan-Min Quan MD, Presenter: Nothing to Disclose

Yang Liu, Abstract Co-Author: Nothing to Disclose

Tao Yuan MD, Abstract Co-Author: Nothing to Disclose

Shengyong Wu MD, PhD, Abstract Co-Author: Consultant, Qmetrics Technologies

To explore the value of the dose reduction technology during lung biopsies with an ultra-low-dose (ULD) protocol. 

A total of ninety consecutive patients (BMI<33kg/m2)who underwent CT-guided (GE lightspeed CT,USA) percutaneous lung biopsy were enrolled and randomised into ULD group(120kV,10mA), low dose group(120kV,50mA)and the standard dose group(120kV,auto-mA); There was no significant difference about lesion features (size, location and the length of the needle path)( P>0.05). Volume CT dose index, dose length product were recorded and the effective dose was calculated.Positive rate of biopsy,the incidences of total complications, incidence of intrapulmonary hemorrhage and the incidence of pneumothorax were also recorded.Radiation doses were compared by using ANOVA; Positive rate of biopsy and the incidences of complications were compared by using chi-square test. 

The effective dose were 0.31±0.07mSv in ULD groups, 2.69±1.34mSv in low dose group, 7.29±2.71mSv in standard dose groups(F=124.16,P=3.25×10-26). The effective dose of ULD groups were 11.5%, 4.3% of the low dose groups and the standard dose groups.The positive rate of biopsy,the total incidences of complications,the incidence of pneumothorax and pulmonary hemorrhage were 86.7%,16.7%,13.3% and 3.3% in ULD groups,93.3%,13.3%,3.3% and 10% in low dose groups,90.0%,16.7%,16.7% and 0% in standard dose groups. The positive rate of biopsy(χ2=0.74, P=0.69),the accuracy in classification and grading of lung cancer(χ2=0.257, P=0.88), the incidences of total complications (χ2=0.17, P=0.92)had no significant difference among three groups. 

Radiation dose during CT-guided percutaneous lung biopsies are reduced greater through the use of a ULD CT protocol without significant difference in technical success and the incidences of complications compared with the low dose groups and the standard dose groups.

Fig.1 Image of a 76-year-old woman (BMI of 24) with squamous cell carcinoma.Low-dose protocol (120KV,50mA).The effective dose was 2.42mSv.Images scoring 5. Fig.2 Image of a 40-year-old man (BMI of 22) with adenocarcinoma.Ultra–low-dose protocol (120KV,10mA).The effective dose was 0.2mSv.Images scoring 5. Fig.3 Image of a 70-year-old man (BMI of 21.8) with adenocarcinoma.Standard dose protocol (120KV,150mA).The effective dose was 4.5mSv.Images scoring 5.  

Quan, G, Liu, Y, Yuan, T, Wu, S, Percutaneous Lung Biopsies Using an Ultra Low-dose Protocol on 16-slice CT: A Preliminary Study Result.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14008562.html