Ye Ju, Presenter: Nothing to Disclose

Ailian Liu MD, Abstract Co-Author: Nothing to Disclose

Yijun Liu, Abstract Co-Author: Nothing to Disclose

Jinghong Liu, Abstract Co-Author: Nothing to Disclose

Renwang Pu MBBCh, FRCPC, Abstract Co-Author: Nothing to Disclose

Longmin Zhang, Abstract Co-Author: Nothing to Disclose

To evaluated the value of spectral CT in differentiating lipid-poor adenomas from metastases in adrenal glands．

This retrospective study was approved by the Institutional Review Board of the participated hospital and written informed consent was waived. From August 2011 to December 2013， 69 patients (49 M: 20 F, mean age=59.4 ± 11.9 years, range 24.0～84.0 years) with 73 adrenal nodules (53 clinically proven metastases and 20 histopathologically proven adenomas) underwent spectral CT imaging through fast kVp-switching technique. The virtual monochromatic images (40～140keV) , fat(water) density images and effective atomic number (eff-Z) were reconstructed. The difference of CT values, fat (water) concentration and eff-Z between adrenal metastases and adenomas were compared statistically by independent-samples t test. 

1) The mean CT values of metastases [(53.00±15.12)～(33.38±5.67) HU] were significantly higher than those of adenomas [(26.90±26.94)～(28.77±10.66) HU] under 40~80 keV level (P<0.05). 2) Fat(water) concentration of metastases (-193.43±173.44 ug/cm3) was statistically lower than that of adenomas (45.32±253.63 ug/cm3) (P<0.05). 3) The eff-Z of metastases (7.76±0.15) was significantly higher than that of adenomas (7.50±0.25) (P<0.05). 

The spectral CT provides a multi-parameter approach for identifying lipid-poor adenomas from metastases.

Lipid-poor metastases and adenomas in adrenal glands could be differentiated through multiple parameters of spectral CT．

Ju, Y, Liu, A, Liu, Y, Liu, J, Pu, R, Zhang, L, The Value of Spectral CT Imaging in Differentiating Lipid-poor Adrenal Adenomas from Metastatic Lesions.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14008369.html