Alice P. Wang, Abstract Co-Author: Nothing to Disclose

Adrienne Frances Thompson MD, Abstract Co-Author: Nothing to Disclose

Yonker Yang Wang MD, Presenter: Nothing to Disclose

Acute CVA in Neonates, as it has significant prognostic implications. This case-based presentation highlights the benefits of rapid 3T MRI exams in detecting neonates with acute CVA,  and how to eveluate Pre-wallerian degeneration.  

The benefits of 3T MRI rapid full neonatal brain imaging of 100 neonates suspected of acute CVA by intracranial US are presented. Wide range of severity of acute ischemic infarct and intraparenchymal hemorrhage cases were detected with MRI exam while neonates were monitored, without sedation. 36 cases of Pre-wallerian degeneration detected. PWD was further defined, its imaging features and prognostic implications discussed. The timeline of the imaging findings related to presentation laid out, in order to highlight the potential of earlier detection of acute CVA and PWD using 3T MRI. Early discovering of neonatal CVA, particularly PWD on MR imaging is key to determining the disease prognosis. Though effective with 1.5 T MRI, its longer acquisition time predisposes the study to motion artefact, necessitating sedation for the study. Our experience shows that MR imaging at 3T is more effective in detecting the critical result of neonatal PWD in patients presenting with acute CVA, while not using any sedation. We favor the use of 3T MRI when to minimize the risk to the neonates undergoing MR imaging.  

http://abstract.rsna.org/uploads/2014/14007910/14007910_cuat.pdf

Wang, A, Thompson, A, Wang, Y, Acute Cerebral Vascular Accident and Pre-wallerian Degeneration in Neonates: The Rapid Full 3 Tesla Magnetic Resonance Imaging of the Brain.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14007910.html