Ulrich Grosse MD, Abstract Co-Author: Nothing to Disclose

Juergen Hetzel, Abstract Co-Author: Nothing to Disclose

Lutz Guendel, Abstract Co-Author: Employee, Siemens AG

Sergios Gatidis MD, Abstract Co-Author: Nothing to Disclose

roland syha, Abstract Co-Author: Nothing to Disclose

Gerd Grozinger MD, Abstract Co-Author: Nothing to Disclose

Christoph Schabel MD, Abstract Co-Author: Speaker, Siemens AG

Claus Detlef Claussen MD, Abstract Co-Author: Nothing to Disclose

Konstantin Nikolaou MD, Abstract Co-Author: Speakers Bureau, Siemens AG Speakers Bureau, Bracco Group Speakers Bureau, Bayer AG

Marius Horger MD, Presenter: Nothing to Disclose

A fundamental knowledge of the pathophysiology of lung emphysema is imperative for understanding the mechanisms of action of the various bronchoscopic lung volume reduction (LVR) techniques. Preinterventional CT imaging of the lung is mandatory to confirm the diagnosis of emphysema, establish the phenotype (heterogeneous vs. homogeneous) as well as to rule out contraindications (for example major fissure gaps for valve-based LVR therapy as they are an indirect sign of collateral ventilation). Quantitative CT assessment of the lung parenchyma can aid in the preinterventional target lobe/ lobes selection and differentiate emphysema from severe bronchial obstruction with hyperinflation (e.g. asthma, bronchiolitis obliterans, etc.). Radiologists should be familiar with the appearance of various LVR-related complications.

Definition, epidemiology & pathophysiology of emphysema Overview of currently used bronchoscopic LVR techniques Detailed presentation of the presumed mechanism of action of LVR- coils & valves and effects on lung volume as well as density Quantification of airflow redistribution Preinterventional imaging Overview Computed tomography including quantitative lung parenchyma analysis Postinterventional imaging LVR- related complications

http://abstract.rsna.org/uploads/2014/14007883/14007883_vovs.pdf

Grosse, U, Hetzel, J, Guendel, L, Gatidis, S, syha, r, Grozinger, G, Schabel, C, Claussen, C, Nikolaou, K, Horger, M, Minimal-invasive Lung Volume Reduction: Bronchoscopic Techniques and Impact of Quantitative CT Emphysema Evaluation.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14007883.html