Gabriela Melendez MD, Presenter: Nothing to Disclose

Guering Eid-Lidt MD, Abstract Co-Author: Nothing to Disclose

Aloha Meave, Abstract Co-Author: Nothing to Disclose

Jorge Ignacio Magana MD, Abstract Co-Author: Nothing to Disclose

Alfredo De Micheli MD, Abstract Co-Author: Nothing to Disclose

Heart failure is a major cause of morbidity and mortality in Acute Myocardial Infarction (AMI) survivors. Ventricular Remodeling (VR) is a major mechanism associated with the development of heart failure. Given the new therapeutic strategies in pharmacological and reperfusion techniques, it is necessary to verify the reliability of previous findings regarding the factors associated with ventricular remodeling.

Ninety-nine consecutive patients with a first reperfused AMI were included. Magnetic Resonance Imaging (MRI) was performed between day 1 and 7 after the AMI and after 3 months, to determine the development of ventricular remodeling. Ventricular remodeling was defined as an increase ≥ 20 % in end-diastolic volume (EDV).

Out of the 97 patients, 23 (23.7 %) had ventricular remodeling. Patients with ventricular remodeling had lower ventricular volumes at the initial MRI compared with patients without remodeling. (EDV 94.9 ± 19.1 ± 27.9 ml vs.118.8 ml, p < 0.001; ESV 48.7 ± 17.5 vs. 62.6 ± 21.4 ml, p = 0.006; and SV 46.2 ± 10.6 vs. 56 ± 15.9, p = 0.006) The EDV was an independent predictor of ventricular remodeling.

Almost a quarter of the patients with a first reperfused AMI had ventricular remodeling. Ventricular volumes calculated at baseline cMR, where lower in patients with ventricular remodeling. EDV was an independent predictor of ventricular remodeling. Further investigation about the mechanism responsible for this phenomenon should be performed. We should have in mind that the improvement in the contemporary medical treatment can modulate the remodeling process after AMI.

To determine the variables that lead to ventricular remodeling after AMI that will allow to identify patients at risk to develop and prevent heart failure.

Melendez, G, Eid-Lidt, G, Meave, A, Magana, J, De Micheli, A, Left Ventricular Volumes Assessed by Cardiac Magnetic Resonance as Predictors of Ventricular Remodeling after Acute Myocardial Infarction.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14007619.html