Takafumi Naka, Presenter: Nothing to Disclose

1) Histopathology of carotid atherosclerotic plaque 2) Magnetic resonance imaging techniques of carotid atherosclerotic plaque 2-1 Comparison and feature of several T1 weighted imaging techniques 3) Relationship between signal hyperintensity on T1WI of carotid atherosclerotic plaque and pathological findings

1) The thickness of the fibrous cap is significantly thinner in symptomaticpatients. Furthermore, plaque ulceration and thrombus formation are more common with symptomatic patients. 2) Althogh electrocardiograph(ECG) gating has been used in conventional imaging technique for carotid atherosclerotic plaque has been used, there is a serious problem that TR changes with the heart rate of the patient. However, 3 dimensional(3D) fast spin echo(FSE) sequence and 3D inversion recovery gradient echo(IR-GRE) sequence dose not have the necessity for ECG gating. In addition, these new imaging techniques make higher in-plane resolution and shorter imaging time possible. 3) Carotid plaque with hyperintensity on T1WI consists of abundant hemorrhage, and lipid core beneath thin fibrous cap. And there are highly correlated with ischemic events.

http://abstract.rsna.org/uploads/2014/14007564/14007564_tubl.pdf

Naka, T, Tissue Characterization of Carotid Atherosclerotic Plaque with Magnetic Resonance (MR) Imaging.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14007564.html