1. Learn appropriate imaging and post processing techniques of Iodine-123-metaiodobenzylguanidine (123I-MIBG) scintigraphy
2. Case-based discussion of 123I-MIBG scintigraphy with correlative radiographic imaging
3. Learn indications of 18F-FDG PET/CT imaging in neuroblastoma
4. Understand the logistic and radiation considerations of 131I-MIBG therapy program
1. Introduction to Neuroblastoma
Clinical presentation, demographics, staging systems
2. Diagnostic 123I-MIBG scintigraphy
a. 123I-MIBG uptake mechanism
b. Indications
c. Patient preparation
d. Imaging technique including advanced image processing
e. Image interpretation
f. Illustrative case examples with different clinical and radiographic presentations
3. Other radionuclide imaging
a. 99mTc-MDP skeletal scintigraphy
b. 18F-FDG PET/CT versus 123I-MIBG scan with illustrative cases
4. 131I-MIBG treatment
a. Background and current status
b. Mechanism of action
c. Design of 131I-MIBG therapy program including radiation safety considerations
d. Treatment procedure
e. Examples of post therapy scans
f. Toxicity
g. Dosimetry
5. Future directions
a. New PET agents
b. Combination therapy
6. Conclusion
Kwatra, N,
Grant, F,
Treves, S,
Radionuclide Imaging and Therapy of Neuroblastoma: A Pictorial Review. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14007543.html