Roberto Llorens Salvador, Presenter: Nothing to Disclose

Francisco Menor, Abstract Co-Author: Nothing to Disclose

Marvin Dale Nelson MD, Abstract Co-Author: Nothing to Disclose

 To show how fetal MR imaging can nicely depict normal and abnormal development of the corpus callosum (CC). To identify the most common disorders affecting the CC in the fetal and neonatal period. To highlight the importance and the impact of perinatal imaging in parental counseling and obstetrical assessment.  

The CC is the largest brain commissure and is related to cognitive functions, social skills, problem solving, and attention. Callosal development starts in 13th week of gestational life and from this time on the CC grows reaching its final shape in week 20, but is still small and grows by addition of fibers and later by myelination,reaching the target volume at the age of 6–9 years. Agenesis and Hypoplasia of the CC constitute the most common pathology. Suspected defects of the corpus callosum should be confirmed by MRI because in 80% of cases they coexist with other CNS pathologies. Assessment of sulcation of the fetal brain is mandatory using prenatal MRI. Callosal abnormalities are found in a great number of other brain malformations(Chiari II malformation, holoprosencephaly,Dandy-Walker).  Although brain sonography can detect callosal disorders, MRI is the method of choice in the assessment of the corpus callosum and its congenital lesions in the perinatal period.  

http://abstract.rsna.org/uploads/2014/14007370/14007370_c16o.pdf

Llorens Salvador, R, Menor, F, Nelson, M, Perinatal Imaging of Developmental Malformation of the Corpus Callosum.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14007370.html