Rosalinda Calandrelli, Presenter: Nothing to Disclose

Gabriella D'Apolito MD, Abstract Co-Author: Nothing to Disclose

Marco Panfili, Abstract Co-Author: Nothing to Disclose

Giuseppe M. Di Lella MD, Abstract Co-Author: Nothing to Disclose

Alessandro Pedicelli MD, Abstract Co-Author: Nothing to Disclose

Tommaso Verdolotti, Abstract Co-Author: Nothing to Disclose

Cesare Colosimo MD, Abstract Co-Author: Nothing to Disclose

• To propose a systematic step-by-step approach to guide the correct diagnostic process in children with brain asymmetry, due to atrophy or hyper-growth of one hemisphere compared to the contralateral one. • To offer some key findings to differentiate the hamartomatous malformations (hemimicroencephaly/ hemimacroencephaly) from the cerebral hemiatrophies (congenital versus acquired), underlying the  complementary role of MRI and CT.

• Introduction to hamartomatous malformations, congenital (Sturge Weber syndrome, Encephalocraniocutaneous Lipomatosis…) and acquired hemiatrophies (trauma, infection, vascular  abnormality, ischemic/hemorrhagic insults). • To illustrate a comprehensive set of MRI and CT key features to help in the diagnosis: 1) Asymmetry of head circumference (hemimacrocrania or hemimicrocrania); bone abnormalities of the skull. 2) Hemispheres asymmetry. 3) Parenchymal abnormalities: alterations of the cortical development, atrophy of white and gray matter, gyral/ subcortical white matter calcifications. 4) Falx position: midline, shifted. 5) Ventricles size: enlarged, normal, dysmorphic. 6)Choroid plexus: enlarged, normal. 7) Post-contrast enhancement: absent, leptomeningeal, dural. 8) Deep venous occlusion: present, absent. 9) Associated findings: “arachnoid cyst”, lipomas. 

http://abstract.rsna.org/uploads/2014/14007353/14007353_hsvn.pdf

Calandrelli, R, D'Apolito, G, Panfili, M, Di Lella, G, Pedicelli, A, Verdolotti, T, Colosimo, C, Brain Asymmetry in Newborns: Radiological Items for a Rational Diagnostic Evaluation. Case Series and Literature Review.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14007353.html