Jinyan Wei, Presenter: Nothing to Disclose

Junlin Zhou, Abstract Co-Author: Nothing to Disclose

To assess the feasibility of virtual non-contrast CT(VNCT) imaging obtained by gemstone spectral imaging(GSI)replacing true non-contrast CT(TNCT) by comparing the image quality and radiation dose and to explore the diagnostic value of VNCT combined with dual-phase contrast enhancement with spectral CT in clear cell renal carcinoma.

Forty patients suspected with clear cell renal cell carcinoma underwent TNCT and dual- phase contrast enhanced CT with GSI mode (Discovery CT 750HD,GE healthcare). The VNCT images were derived from the data of cortex phase using a dedicated software(GSI Volume Viewer). Between the TNCT and VNCT, the noise, the CT HU values of mass, and the total dose length product (DLP) were compared with t test and the diagnostic sensitivity was compared with χ2 test. The diagnostic accuracies of clear cell renal carcinoma between conventional renal triple-phase and VNCT combined dual-phase contrast enhancement CT was compared with χ2 test.

VNCT had higher image noise than TNCT [12.33±0.46 vs 14.31±0.29，t=-3.63，P<0.01]. The mean CT HU values of tumors on VNCT images were similar with that of TNCT images [（36.02±1.23）HU vs（32.23±1.88）HU，t=-1.687，P>0.05]. Diagnostic sensitivity of VNCT was compatible with that of TNCT[91.69％、93.67％，P>0.05]. The total radiation dose of DLP in dual-phase contrast enhancement CT [(408.14±38.24)mGy·cm)]was lower than that of conventional renal triple-phase [(624.21±68.12)mGy·cm]，P<0.01. Diagnostic accuracies of clear cell renal carcinoma between conventional renal triple-phase and VNCT combined dual-phase contrast enhancement CT had no significant difference (94.2% and 93.5%，P>0.05).

GSI dual-phase imaging in renal will be a good substitute since the radiation can be greatly reduced compared with traditional triple-phase imaging and the diagnostic accuracy of clear cell renal carcinoma maintains.

Virtual non-contrast CT of GSI may substitute true non-contrast CT by reducing radiation dose and maintains the diagnostic accuracy of disease.

Wei, J, Zhou, J, The Value of Virtual Non-contrast with Spectral CT in Clear Cell Renal Carcinoma of Triple-phase.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14007253.html