Young Keun Sur MD, Presenter: Nothing to Disclose

Young Chul Kim MD, Abstract Co-Author: Nothing to Disclose

Eun Ju Ha, Abstract Co-Author: Nothing to Disclose

Seon Young Park MD, Abstract Co-Author: Nothing to Disclose

Jei Hee Lee MD, Abstract Co-Author: Nothing to Disclose

Jai Keun Kim MD, Abstract Co-Author: Nothing to Disclose

To compare diagnostic feasibility between endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) using 25-gauge (G) needle and ultrasound-guided percutaneous core needle biopsy (USG-CNB) using 18 G core needle for the diagnosis of solid pancreatic lesion.

This retrospective study was approved by our institutional review board and the requirement for informed consent was waived. Patients who underwent either EUS-FNA or USG-CNB for solid pancreatic lesion from January 2008 to December 2012 were included and reviewed. EUS-FNAs and USG-CNBs were performed by experienced endoscopists or radiologists. Technical failure rate, diagnostic accuracy, sensitivity, and specificity for malignancy were calculated and compared.

One hundred seven biopsy attempts were undertaken in 89 patients (EUS-FNA, n=71; USG-CNB, n=36). Biopsy specimens were successfully obtained in 99 biopsy attempts (EUS- FNA, n=64; USG-CNB, n=35). The technical failure rate of EUS-FNA and USG-CNB was 9.86% and 2.78%, respectively (p=0.3541). Sensitivity and specificity of EUS-FNA for malignancy was 76.36% and 88.89%, respectively, which was not significantly different (p=0.3588 and 0.6645, respectively) from sensitivity and specificity of USG-CNB (87.09% and 100%, respectively). Diagnostic accuracy was 78.13% in EUS-FNA and 88.57% in USG-CNB, which was also not significantly different (p=0.3101). Diagnostic accuracy did not differ between the two modalities according to the location of the lesion in pancreas.

The similar diagnostic performance of EUS-FNA and USG-CNB supports the use of the two modalities as a complementary utility for the accurate diagnosis of solid pancreatic lesions.

Accurate diagnosis of lesions as benign or malignant should help clinicians establish proper treatment plans and avoid unnecessary surgery.

Sur, Y, Kim, Y, Ha, E, Park, S, Lee, J, Kim, J, Comparison of Diagnostic Feasibility between Ultrasound-guided Percutaneous Core Needle Biopsy and Endoscopic Ultrasound-guided Fine Needle Aspiration for Solid Pancreatic Lesions.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14006975.html