Ann Yi MD, PhD, Presenter: Nothing to Disclose

Nariya Cho MD, Abstract Co-Author: Nothing to Disclose

Kyung-Sook Yang PhD, Abstract Co-Author: Nothing to Disclose

Woo Kyung Moon, Abstract Co-Author: Nothing to Disclose

To investigate the effect of preoperative breast MRI on disease-free survival (DFS) outcomes in newly diagnosed breast cancer patients.

Between 2004 and 2006, we identified 2040 consecutive breast cancer patients (median age, 54.5; range, 20 - 89 years) who had undergone curative surgery for breast cancer (stage 0, 270; I, 734; II, 795; III, 241). Among them, 1597 (78.3%) underwent preoperative MRI (MRI group) and 443 (21.7%) did not (non-MRI group). A total of 330 women of the MRI group were able to be matched with 330 women of the non-MRI group (both groups, median age, 51.2; range, 20 – 81 years) for age, menopausal status, tumor size, histologic type, histologic/nuclear grade, hormonal receptor status, molecular subtype, lymphovascular invasion, resection margin status, nodal status, pathologic stage, surgery type, and adjuvant treatment. A marginal model was used for the matched cohort to evaluate the effect of preoperative MRI on DFS. Kaplan-Meier survivals were also compared between MRI and non-MRI groups using the log-rank test.

The effect of preoperative MRI on DFS was not statistically significant (hazard ratio, 1.25; P=0.282). Kaplan-Meier survival was not significantly different between MRI and non-MRI groups (log-rank, 1.22; P=0.338).

DFS outcome is not significantly different between MRI and non-MRI groups in the matched cohort of newly diagnosed breast cancer patients.

Routine application of preoperative MRI for newly diagnosed breast cancer patients is not recommended as no additional benefit in DFS of the MRI group was observed in our matched cohort study.

Yi, A, Cho, N, Yang, K, Moon, W, Survival Outcomes of Newly Diagnosed Breast Cancer Patients with and without Preoperative Breast Magnetic Resonance Imaging: Matched Cohort Study.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14006881.html