Ybao Liu MD, PhD, Presenter: Nothing to Disclose

Fatih Akisik MD, Abstract Co-Author: Nothing to Disclose

Kumaresan Sandrasegaran MD, Abstract Co-Author: Nothing to Disclose

Temel Tirkes MD, Abstract Co-Author: Nothing to Disclose

Mark Tann MD, Abstract Co-Author: Nothing to Disclose

Chang Hong Liang MD, Abstract Co-Author: Nothing to Disclose

Chen Lin PhD, Abstract Co-Author: Research Grant, Siemens AG

To retrospectively investigate the value of MRCP in detecting wirsungocele and santorinicele, correlation with chronic or acute pancreatitis, as well as comparison with ERCP and EUS results.

This retrospective HIPAA-compliant and IRP proven study, with waiver of informed consent, included 80 patients (61 santoriniceles, 18 wirsungoceles and 1 both santorinicele and wirsungocele).14 of 80 patients underwent only MRCP exams while 66 of 80 patients underwent S-MRCP exams. Analyzing the sizes of santorinicele and wirsungocele, comparing the sensitivity and specificity of MRCP and S-MRCP in detecting santorinicele and wirsungocele, analyzing whether santorinicele and wirsungocele are correlated with pancreas divisum, chronic or acute pancreatitis, and compared the results with ERCP and EUS findings.Statistical analysis included χ2 test, Fisher’s exact probability procedures. A value of p<.05 was considered significant.

The study subjects consisted of 80 patients (21 male and 59 female; mean age at time of diagnosis, 55 years; range, 11-82 years). Size of wirsungocele (N=18) 4.5 ± 1.7 mm and santorinicele (N=62) 3.6 ± 0.8 mm. There was significant difference between MRCP and S-MRCP in detecting santorinicele, 68 % and 92 % (p ＜.05), and wirsungocele was 52 % and 99 % (p ＜.05).  There was a significant correlation between santorinicele and chronic pancreatitis, 51% had chronic pancreatitis, and 8 % had acute pancreatitis. 11% wirsungocele patients had chronic pancreatitis and none had clinical diagnosis of acute pancreatitis. 

MRCP is useful in identifying wirsungocele and santorinicele. Secretin increases the sensitivity of the exam. Chronic or acute pancreatitis are more common in the patient with a santorinicele than in a patient with a wirsungocele.

The diagnosis of santorinicele is important as there is a correlation with acute and chronic pancreatitis as opposed to a wirsungocele.

Liu, Y, Akisik, F, Sandrasegaran, K, Tirkes, T, Tann, M, Liang, C, Lin, C, Wirsungocele and Santorinicele: MRCP Findings and Clinical Outcomes.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14006841.html