David Zander MD, Presenter: Nothing to Disclose

Sanjay Padubidri Prabhu MBBS, Abstract Co-Author: Nothing to Disclose

Ellen Grant MD, Abstract Co-Author: Nothing to Disclose

Edward Yang MD, PhD, Abstract Co-Author: Research Consultant, CorticoMetrics LLC

Borjan Gagoski PhD, Abstract Co-Author: Nothing to Disclose

Richard Lee Robertson MD, Abstract Co-Author: Nothing to Disclose

The purpose of the exhibit is to: 1. Briefly review the concept of tissue perfusion. 2. Provide an overview of current methods of measuring cerebral perfusion, highlighting pros and cons in the pediatric population. 3. Define arterial spin labeling, illustrate labeling schemes, and describe technical aspects of performing the exam. 4. Detail the variety of arterial spin labeling applications in neuroimaging, with emphasis on unique utility within the pediatric population.

+What is perfusion, and how do we measure it? +Comparison of current cerebral perfusion methods -Exogenous diffusible tracers -Exogenous non-diffusible tracers +Endogenous tracers +Define arterial spin labeling (ASL) +Technical methods of ASL -Continuous ASL -Pulsed ASL -Pseudocontinuous ASL -3D ASL -Technical aspects unique to pediatric population +Sample cases -Hypoperfusion .Stroke .Diffuse cerebral edema .Tumor .Tuberous Sclerosis .Moya Moya .Hemiplegic migraine -Hyperperfusion .Hypoxic injury (profound and partial) .Infection .Epilepsy (peri-ictal) .Posterior reversible encephalopathic syndrome .Tumor .Heterotopia .Mitochondrial disorders .Arteriovenous shunting -Perfusion territory imaging +Normal variants and artifacts +Future directions/Summary

http://abstract.rsna.org/uploads/2014/14006773/14006773_29yi.pdf

Zander, D, Prabhu, S, Grant, E, Yang, E, Gagoski, B, Robertson, R, Arterial Spin Labeling and its Application in Pediatric Neuroimaging.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14006773.html