Limin Yang MD, PhD, Presenter: Nothing to Disclose

Jeong Mi Park MD, Abstract Co-Author: Nothing to Disclose

Laurie Lee Fajardo MD, MBA, Abstract Co-Author: Scientific Advisory Board, Hologic, Inc Scientific Advisory Board, Koninklijke Philips NV

Recognition of nonmalignant architectural distortion imaging findings on Tomosynthesis will help to distinguish benign from subtle malignant architectural distortion & reduce false positive biopsy rate.

Tomosynthesis detects both benign & malignant architectural distortion that is occult on 2D mammography. Being familiar with imaging features of benign & malignant architectural distortion can reduce false positive biopsy rate for benign architectural distortion. We demonstrate imaging features of 9 patients with nonmalignant architectural distortion detected on Tomosynthesis (occult on 2D mammogram) & correlate with pathology. Six were radial scar/sclerosing complex lesions & 3 were sclerosing adenosis. Nonmalignant architectural distortion tends to be more symmetrically distributed without central high density & may be stable from prior studies, while malignant architectural distortion tends to be bigger in size, asymmetrically distributed with irregular central high density. The majority of nonmalignant architectural distortions are small in size & difficult to detect or subtle on ultrasound. Distinguishing imaging features between benign & subtle malignant architectural distortion may permit recommendation for 6 month followup rather than biopsy, improving specificity & accuracy of breast cancer screening with tomosynthesis.

http://abstract.rsna.org/uploads/2014/14006726/14006726_8vma.pdf

Yang, L, Park, J, Fajardo, L, Nonmalignant Architectural Distortion Detected only by Tomosynthesis: Imaging Findings, Pathological Correlation and Clinical Significance.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14006726.html