Yoko Kaichi, Presenter: Nothing to Disclose

Toru Higaki PhD, Abstract Co-Author: Nothing to Disclose

Chihiro Tani MD, Abstract Co-Author: Nothing to Disclose

Yuko Nakamura MD, Abstract Co-Author: Nothing to Disclose

Fuminari Tatsugami, Abstract Co-Author: Nothing to Disclose

Kazuo Awai MD, Abstract Co-Author: Research Grant, Toshiba Corporation Research Grant, Hitachi Ltd Research Grant, Bayer AG Research Consultant, DAIICHI SANKYO Group Research Grant, Eisai Co, Ltd

1. The clinical utility of ASL, a noninvasive neuroimaging modality, for the objective assessment and differential diagnosis of neuropsychiatric deficits in depressed patients. Although some diseases eliciting depression share neuropsychiatric features, their regional cerebral blood flow (rCBF) distribution is different. 2. Some depressed patients manifest carotid artery stenosis. As the delayed arterial transit effect may result in the retention of labeled arterial blood in the feeders, this must not be misinterpreted as increased rCBF. The presence of extra-axial lesions must be considered.

1. Interpretation of ASL in depressed patients - principles of ASL - rCBF distribution in depressed patients 2. Value of ASL for evaluating the severity of depression - correlation between rCBF and depression severity 3. Value of ASL for the differential diagnosis of diseases that may produce depression - comparison of the rCBF distribution in patients with transient hypothyroidism, major depressive disorder, and the controls 4. Value of ASL for predicting the response to antidepressants - comparison of the rCBF distribution in patients with refractory- and responsive depressive disorder 5. Value of ASL for the assessment of cure from depression 6. Diagnostic pitfalls in readings of ASL

http://abstract.rsna.org/uploads/2014/14006509/14006509_1sio.pdf

Kaichi, Y, Higaki, T, Tani, C, Nakamura, Y, Tatsugami, F, Awai, K, Clinical Utility and Pitfalls of Arterial Spin Labeling (ASL) in Depressed Patients.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14006509.html