Sherif Abdelfattah MD, PhD, Presenter: Nothing to Disclose

Hassan Kassem MD, Abstract Co-Author: Nothing to Disclose

To evaluate the diagnostic impact of echo planar DW imaging in distinguishing benign from malignant musculoskeletal soft-tissue masses using ADC mapping as a quantitative assessment tool.  

We evaluated 73 tumors (21 bone tumors and 52 soft-tissue tumors). MR examinations were performed with a 1.5-T system. Diffusion-weighted single-shot EPI images were obtained in all patients. Apparent diffusion coefficients (ADCs) were calculated by using b factorsof 0 and 1000 s/mm2. ADC value measurements were compared with the histopathological findings.  

The average ADC of benign tumors was 1.86 ±0.67 • 10_3 mm2/s, and that of malignant soft-tissue tumors was 0.97 ±0.35 • 10_3 mm2/s. ADC value of malignant tumors was significantly lower than that of the benign tumor group (p< 0.0001). The highest ADC value was seen in the case of ganglion cyst (2.8 ± 0.23 • 10_3 mm2/s) and cystic neurofibroma (2.5 ± 0.04 • 10_3 mm2/ s), and juxta cortical enchondroma (2.65 ± 0.36 • 10_3 mm2/s) while the lowest one was seen in aggressive fibromatosis (0.37± 0.05 • 10_3 mm2/s). For malignant soft-tissue masses, the highest ADC value was seen in mesenchymal chondrosarcoma (2.1 ± 0.32) liposarcoma (intermediate grade) (1.4 ± 0.21) while the lowest ADC value was seen in fibrosarcoma (high grade) (0.78± 0.14).  

MR diffusion provides additional information to the routine MRI sequences rendering it an effective non-invasive tool in differentiating between benign and malignant soft-tissue tumors

MR diffusion provides additional information to the routine MRI sequences rendering it an effective non-invasive tool in differentiating between benign and malignant soft-tissue tumors

Abdelfattah, S, Kassem, H, Diagnostic Impact of Echo Planar Diffusion-weighted Magnetic Resonance Imaging (DWI) in Musculoskeletal Neoplastic Masses Using Apparent Diffusion Coefficient (ADC) Mapping as a Quantitative Assessment Tool  .  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14006452.html