Govind Babusing Chavhan MD, Presenter: Nothing to Disclose

Paul S. Babyn MD, Abstract Co-Author: Nothing to Disclose

Paul Nathan MD, FRCPC, Abstract Co-Author: Nothing to Disclose

Sue Creviston Kaste DO, Abstract Co-Author: Nothing to Disclose

1. Effects of cancer therapy in children can be seen in early survival period or later in life in almost all organ systems of the body. 2. Many of these conditions are evaluated by imaging and some are diagnosed based on characteristic imaging features.  

Introduction Common therapy options in childhood cancers Early (during therapy) and late (after end of therapy) effects of cancer therapy Therapy related conditions with illustration of imaging features in various systems : - Endocrine system- Hypothyroidism, Growth Hormone deficiency, short stature BMD deficits, delayed bone age - Pulmonary- Interstitial lung disease, parenchymal alterations, fibrosis, scarring, volume loss - Hepatobiliary- Focal nodular hyperplasia, cholelithiasis, fibrosis, iron deposition - Genitourinary- Renal atrophy, hemorrhagic cystitis, acquired vaginal occlusion - MSK- Osteonecrosis, GCSF related marrow changes, marrow conversion, osteoporosisbone mineral density deficits , scoliosis, myositis., osteochondromas, radiation osteitis, premature physeal closure, asymmetric physeal closure, marrow fibrosis, post XRT growth disturbances, asymmetric growth - Multisystem- GVHD, PTLD, Secondary malignancies Summary and Teaching points References

http://abstract.rsna.org/uploads/2014/14006124/14006124_suao.pdf

Chavhan, G, Babyn, P, Nathan, P, Kaste, S, Imaging of Early and Late Effects of Cancer Therapy in Children.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14006124.html