Chris Somerville MD, Presenter: Nothing to Disclose

Mitchell E. Tublin MD, Abstract Co-Author: Nothing to Disclose

- Only one fatty abnormality of the pancreas is common – fatty parenchymal replacement. Some of its many variations can mimic other fatty lesions.  - All other fatty pancreatic lesions are rare. - Focal fatty replacement can mimic a lipoma. Near-complete fatty atrophy can be difficult to differentiate from lipomatous pseudohypertrophy. However, these distinctions are academic, as all are incidental findings. - Fat does not occur in adenocarcinoma, neuroendocrine tumors, or cystic neoplasms of the pancreas.  - Liposarcoma is the only malignant fat-containing lesion of the pancreas. It is exceedingly rare.  - Any fatty abnormality of the pancreas containing homogenous fat and no solid or enhancing components is an incidental finding. 

- Intro   o Fat on CT, MR, US   o regional anatomy of pancreas - Fatty replacement   o Partial – diffuse, focal   o Complete     - atrophy     - enlargement – cystic fibrosis, lipomatous pseudohypertrophy, Shwachman-Diamond Syndrome, duct obstruction - Masses   o Hypoplasia   o Lipoma   o Liposarcoma   o Teratoma   o Angiomyolipoma/PEComa  - Work-up and clinical significance

http://abstract.rsna.org/uploads/2014/14005193/14005193_cri8.pdf

Somerville, C, Tublin, M, Fat-Containing Lesions of the Pancreas.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14005193.html