Gunes Orman MD, Presenter: Nothing to Disclose

Izlem Izbudak MD, Abstract Co-Author: Nothing to Disclose

The purpose of this exhibit is: 1. To review the pathophysiology and history of neuromyelitis optica (NMO) 2. To emphasize that majority of NMO patients have brain lesions over the course of the disease and approximately 70% of brain lesions are characteristic for NMO 3. To demonstrate multiple types of brain lesions shown to be characteristic for NMO on brain MRI   

History of NMO Pathophysiology of NMO and Recent Discoveries Review of Brain MRI Findings – Conventional MRI: • T2 and FLAIR sequences (periependymal lesions surrounding aqueduct, third and fourth ventricles, diencephalon and brainstem lesions, longitudinally extensive corticospinal tract lesions, extensive hemispheric white matter lesions, nonspecific lesions) • Post-contrast T1 sequence (periependymal, cloud-like, leptomeningeal, isolated, ring enhancement) – Diffusion Weighted Imaging Sample cases and mimics Future directions and summary  

http://abstract.rsna.org/uploads/2014/14004953/14004953_9tsz.pdf

Orman, G, Izbudak, I, “Neuromyelitis Optica” Evokes Merely Optic Neuritis and Transverse Myelitis, but Are We Ignoring Brain Lesions?.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14004953.html