1. Diffusion weighted imaging (DWI) is a functional non-contrast MRI technique that adds little time to a routine soft tissue mass MR imaging protocol.
2. Soft tissue masses can be categorized by their different imaging patterns on quantitative DWI with apparent diffusion coefficient (ADC) mapping.
3. ADC values obtained by quantitative DWI often correspond with the histologic composition of tumors, and non-neoplastic soft tissue masses have a variable appearance that can mimic tumors.
1. Review of the literature on quantitative DWI for the characterization of soft tissue masses
Systematic review: Characterization for malignancy
2. Appraisal of available DWI techniques for imaging
Impact on ADC values of soft tissue masses
3. Quantitative DWI patterns in soft tissue masses
a. Non-neoplastic processes
i. Hematoma
ii. Myositis Ossificans
iii. Abscess
iv. Soft tissue cysts:
Ganglion, lymphocele, seroma
v. Post-operative nodular scar
b. Neoplasms:
i. Adipocytic
ii. Fibroblastic/Myofibroblastic
iii. So-Called Fibriohistiocytic
iv. Smooth Muscle
v. Skeletal Muscle
vi. Vascular
vii. Gastrointestinal Stromal
viii. Peripheral Nerve Sheath
ix. Tumors of Uncertain Differentiation
x. Undifferentiated/Unclassified Sarcoma
Ahlawat, S,
Demehri, S,
Fayad, L,
Patterns in Quantitative Diffusion-weighted Imaging of Soft Tissue Masses That Are Associated with Different Histologies. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14004935.html