Shivani Ahlawat MD, Presenter: Nothing to Disclose

Jaishri Blakely MD, Abstract Co-Author: Nothing to Disclose

Laura Marie Fayad MD, Abstract Co-Author: Nothing to Disclose

1. To review the current literature on the use of whole body magnetic resonance imaging (Wb-MRI) in patients with peripheral nerve sheath tumor syndromes, particularly neurofibromatosis types 1 and 2, and schwannomatosis 2. To emphasize differences in technical parameters offered at 1.5T and 3T. 3. To describe the utility of WB-MRI for tumor detection (assessment of disease burden), characterization of peripheral lesions, and evaluation of treatment response in patients with peripheral nerve tumor syndromes.  

• Review of Wb-MRI Techniques in current use o 1.5 T v 3.0 T o 2-Dimensional versus 3-Dimensional Imaging o Anatomic sequences  T1 weighted  Fluid sensitive STIR  Static post contrast images o Functional Sequences  Diffusion Weighted Image with Apparent Diffusion Coefficient Maps o Quantification of PNST size  2-Dimensional (RECIST criteria) versus volumetric Analysis • Utility of Whole Body MRI inPNST syndromes o Detection  Whole body benign PNST tumor burden • Mosaicism  Skeletal muscle denervation o Characterization  Distinguish PNST from perineural cyst  Differentiate PNSTs • Benign o Solitary o Plexiform • Malignant o Treatment response • Assessment of tumor burden following treatment  

http://abstract.rsna.org/uploads/2014/14004927/14004927_becb.pdf

Ahlawat, S, Blakely, J, Fayad, L, Whole Body MRI in Peripheral Nerve Sheath Tumor Syndromes: A Systematic Review.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14004927.html