Tyson Steven Chadaz MD, Abstract Co-Author: Nothing to Disclose

Brett S. Talbot MD, Presenter: Nothing to Disclose

Johnny Uzoma Valmon Monu MD, Abstract Co-Author: Nothing to Disclose

The purpose of this educational exhibit is to: 1. Reiterate awareness of unsuspected and unexpected effect of drugs on patients’ bones 2. Demonstrate a series of challenging musculoskeletal cases with common and uncommon medication-related changes. 3. Review the pertinent literature on adverse medication effects on bone. 

Specific cases include: Osteonecrosis of the jaw associated with zoledronic acid Bisphosphonate associated femur fractures Osteosclerosis associated with numerous agents. Bone marrow changes associated with granulocyte-colony stimulating factor   Demineralization associated with numerous agents including: -Glucocorticoids -Inhaled corticosteroids -Heparin -Selective serotonin reuptake inhibitors/tricyclic antidepressants -Chemotherapeutic agents -Aromatase inhibitors -Thiazolidinediones -Antiepileptic drugs -Cyclosporine -GnRH agonists/antagonists -Loop diuretics

http://abstract.rsna.org/uploads/2014/14004723/14004723_x1df.pdf

Chadaz, T, Talbot, B, Monu, J, Bones on Drugs: Imaging of Drug-Related Changes in Bone.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14004723.html