Ronald William Mercer BA, Presenter: Nothing to Disclose

Teresa Martin-Carreras BS, Abstract Co-Author: Nothing to Disclose

Nicholas Paul McKenna BA, Abstract Co-Author: Nothing to Disclose

Laura W. Bancroft MD, Abstract Co-Author: Royalties, Wolters Kluwer nv

Steven Anthony Messina MD, Abstract Co-Author: Nothing to Disclose

(1) Intracranial abnormalities in pediatric patients diagnosed with sickle cell disease  include vascular stenosis/occlusion, moyamoya, cerebral atrophy, gliosis, non-hemorrhagic infarcts in large vascular and watershed distributions, postoperative changes after pial synangiosis, and osseous cranial abnormalities . (2) Transcranial sonography, computed tomography (CT), magnetic resonance imagin (MRI), MR angiography and conventional angiography provide valuable diagnostic information in the pre- and postoperative pediatric sickle cell patient.

►Introduction to CNS changes in pediatric patients with sickle cell disease ►Discuss common clinical indications for imaging studies in sickle cell patients ordered to assess the CNS ►Review imaging findings and discuss their prevelance in this population of patients: - Vascular stenoses, occlusion and moyamoya - Acute and chronic ischemic changes. Specifically, the common areas involved (e.g. watershed versus lacunar infarcts) - Cerebral atrophy and encephalomalacia - Postoperative changes from pial synangiosis - Osseous cranial abnormalities ►Future directions and summary 

http://abstract.rsna.org/uploads/2014/14004635/14004635_k85o.pdf

Mercer, R, Martin-Carreras, T, McKenna, N, Bancroft, L, Messina, S, Intracranial Lesions in Pediatric Patients with Sickle Cell Disease: A Review of Imaging Findings.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14004635.html