Bernd Friedrich Daeubler MD, Presenter: Nothing to Disclose

Val Murray Runge MD, Abstract Co-Author: Speaker, Bayer AG Speaker, Bracco Group

Michael Wyss, Abstract Co-Author: Nothing to Disclose

Mike Bruegger, Abstract Co-Author: Nothing to Disclose

Daniel Nanz PhD, Abstract Co-Author: Nothing to Disclose

Pinar Oezbay, Abstract Co-Author: Nothing to Disclose

Klaas P. Pruessmann, Abstract Co-Author: Nothing to Disclose

Spyros Sotirios Kollias MD, Abstract Co-Author: Nothing to Disclose

1. High resolution, heavily T1- and T2*-weighted images at 7T provide anatomic recognition of structures in the brainstem and cerebellum not previously possible on MR. 2. Illustration of anatomical detail at 7T facilitates translation of this knowledge to 3T, with potential improvements in diagnosis and correlation of clinical symptoms.

Two high-resolution 3D sequences were acquired at 7T (Philips Healthcare), in the axial plane, of the brainstem and cerebellum in each of 24 volunteers, with voxel dimensions of (0.65 mm)x3. The first was a T1-weighted IR MP-RAGE scan, with TI selected to further improve gray-white matter differentiation, TR/TE/TI/flip angle = 12/5.8/850/7°, iPAT=1.5, 126 Hz BW, 2 NSA, and 15:34 min:sec scan time (this was also acquired in the sagittal plane in 8 volunteers). The second was a T2*-weighted multiecho GRE scan, with subsequent reconstruction of an R2* map. 10 echoes were acquired (TE of 5 to 50), with TR/flip angle = 60/18°, iPAT=2, 580 Hz BW, 1 NSA, and 12:52 min:sec scan time. These data sets were correlated with two anatomic atlases, Duvernoy's Atlas of the Human Brain Stem and Cerebellum and An Atlas of the Basal Ganglia, Brain Stem and Spinal Cord, Based on Myelin-Stained Material. The presentation focuses on identification of brainstem and cerebellar structures thus visualized.

http://abstract.rsna.org/uploads/2014/14004010/14004010_yc68.pdf

Daeubler, B, Runge, V, Wyss, M, Bruegger, M, Nanz, D, Oezbay, P, Pruessmann, K, Kollias, S, High Resolution Imaging in Vivo of the Brainstem and Cerebellum at 7T, Focusing on Identification of Normal Anatomy, White Matter Tracts, and Nuclei.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14004010.html