Darel Edward Heitkamp MD, Presenter: Nothing to Disclose

Wahida Tania Rahman MD , Abstract Co-Author: Nothing to Disclose

Shawn D. Teague MD, Abstract Co-Author: Nothing to Disclose

Karen M. Rieger MD, Abstract Co-Author: Nothing to Disclose

Kenneth A. Kesler MD, Abstract Co-Author: Nothing to Disclose

1. Primary mediastinal nonseminomatous germ cell tumor (PMNSGCT) typically occurs in a predictable location within the thorax.  This exhibit will familiarize the radiologist with the appearance of classic and atypical PMNSGCTs.  2. Radiology plays a vital role in the diagnosis and pre-surgical planning of these patients, as well as the post-surgical evaluation of potential complications and disease recurrence.  3. PMNSGCT represents a challenging subgroup of malignant germ cell tumors and survival depends on both sucessful chemotherapy and surgical resection.  4. An aggressive multidisciplinary approach that includes surgery after cisplatin-based chemotherapy can result in long-term survival, even in patients with persistent germ cell or non-germ cell cancer.

1. Introduction: basic information related to PMNSGCT.  2. Current treatment paradigm (chemotherapy + surgery).   The crucial role of radiology in diagnosis and treatment planning.  Review of surgical approach and how it affects imaging appearance.  3. Imaging review of classic and atypical cases.  Pretherapy and posttherapy appearance.  Recurrence and posttherapy salvage cases.  Imaging of surgical devices and common complications.  4. Review of extensive single institution data including independent predictors of survival.

http://abstract.rsna.org/uploads/2014/14003936/14003936_4nwa.pdf

Heitkamp, D, Rahman, W, Teague, S, Rieger, K, Kesler, K, Radiologic Review of Primary Mediastinal Nonseminomatous Germ Cell Tumors: Three Decades of Experience from a Large Referral Center with Emphasis on Surgical Management.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14003936.html