Daria Manos MD, FRCPC, Presenter: Author, Springer Science+Business Media Deutschland GmbH

Joy Nina Borgaonkar MD, FRCPC, Abstract Co-Author: Nothing to Disclose

1. At least 75% of persistent ground glass opacities represent atypical adenomatous hyperplasia or adenocarcinoma in situ. 2. Management of persistent ground glass opacities is controversial and resection of ground glass neoplasm has been criticized for contributing to overdiagnosis in CT screening. 2. The 5-year prognosis for resected adenocarcioma in situ is 100%. 3. Pure ground glass neoplasm typically grows slowly but can progress to invasive adenocarcinoma. Worrisome CT features include large size, rate of growth, increase in density and association with an irregular lung cyst. 4. The decision to resect a ground glass opacity should be made on an individual basis with consideration of the nodule characteristics, the risks of surgery and competing causes of death in the next 5 years.

1. Differential of focal ground glass opacity on CT 2. Natural history of persistent ground glass opacities; what is known, what is unknown. 3. Work up options for ground glass opacities. 4. Illustration of teaching points including a case series of 20 tissue-proven adenocarcinomas originally appearing on CT as ground glass opacities. All cases have serial CT documenting CT behavior over 5 to 12 years. 5. Risks and benefits regarding the resection of ground glass neoplasm. 

http://abstract.rsna.org/uploads/2014/14003790/14003790_dga4.pdf

Manos, D, Borgaonkar, J, Long Term CT Follow Up of Ground Glass Opacities Progressing to Invasive Adenocarcinoma: A Review and Case Series.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14003790.html