Ameya Jagadish Baxi MBBS, DMRD, Presenter: Nothing to Disclose

Carlos S. Restrepo MD, Abstract Co-Author: Nothing to Disclose

Amy Laura Mumbower MD, Abstract Co-Author: Nothing to Disclose

Michael James McCarthy MD, Abstract Co-Author: Nothing to Disclose

Rashmi S. Katre, Abstract Co-Author: Nothing to Disclose

Santiago Martinez-Jimenez MD, Abstract Co-Author: Author, Amirsys, Inc

Ashish Rajendra Khandelwal MD, Abstract Co-Author: Nothing to Disclose

Aleema Patel MD, Abstract Co-Author: Nothing to Disclose

1. Study the pathophysiology of Mounier-Kuhn Syndrome 2. Study radiological spectrum and differential diagnosis

Mounier-Kuhn syndrome is characterized by tracheobronchial dilation due to atrophy of muscular and elastic tissues in trachea and main bronchial walls. It usually presents with recurrent pneumonias, fibrosis and other respiratory complications of pooled/stagnant secretions in dilated airways. Diagnosis of tracheal dilatation is often made by plain radiography although CT is more sensitive. In adults, the diagnostic criteria are: diameter of the trachea >30 mm; of the right main bronchus >20 mm; and of the left main bronchus >18 mm. MK syndrome has 3 subtypes. In type 1, there is a slight symmetric dilation in the trachea and main bronchi; in type 2, the dilation and diverticula are distinct; and in type 3, diverticular and saccular structures extend to distal bronchi.The other conditions which may cause tracheobronchial dilatation include: connective-tissue diseases, ataxia-telangiectasia, ankylosing spondylitis,Ehlers-Danlos syndrome, Marfan’s syndrome,Kenny-Caffey syndrome,Brachmann-de Lange syndrome, and cutis laxa.These diseases differ in epidemiology, clinical outcome, management and prognosis. Radiologists should be familiar with the imaging appearances of MK syndrome and understand its clinical significance.      

http://abstract.rsna.org/uploads/2014/14003784/14003784_d34m.pdf

Baxi, A, Restrepo, C, Mumbower, A, McCarthy, M, Katre, R, Martinez-Jimenez, S, Khandelwal, A, Patel, A, Mounier-Kuhn Syndrome: Radiological Spectrum with Differential Diagnosis.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14003784.html