Ameya Jagadish Baxi MBBS, DMRD, Presenter: Nothing to Disclose

Carlos S. Restrepo MD, Abstract Co-Author: Nothing to Disclose

Gregg William Bean MD, Abstract Co-Author: Nothing to Disclose

Amy Laura Mumbower MD, Abstract Co-Author: Nothing to Disclose

Michael James McCarthy MD, Abstract Co-Author: Nothing to Disclose

Rashmi S. Katre, Abstract Co-Author: Nothing to Disclose

Mateen Siddiqui MBBS, Abstract Co-Author: Nothing to Disclose

1. To study thoracic manifestations of sickle cell disease 2. To discuss the role of imaging in the diagnosis and evaluation of suspected complications of sickle cell disease 3. To differentiate manifestations of sickle cell disease from diseases having similar radiological appearances  

Patients with sickle cell anemia frequently develop pulmonary complications due to slow progressive decline in pulmonary function. Though it affects multiple organs, pulmonary complications are the prime cause of morbidity and mortality in sickle cell disease. Pulmonary manifestations can be divided into acute and chronic. The acute manifestations include acute chest syndrome, asthma, pneumonia, thromboembolism and left ventricle failure. Chronic manifestations include cardiomegaly, pulmonary edema, pleural effusion, pulmonary fibrosis and pulmonary hypertension. In addition, patients with sickle cell disease frequently suffer from skeletal manifestations which include bone necrosis, osteomyelitis, extramedullary hematopoiesis, osteopenia and pathologic fractures. Many of these manifestations have a distinct radiological appearance on plain radiographs, CT scans and MRI.  A timely and accurate radiological diagnosis of thoracic manifestations and complications of sickle cell may have significant impact on treatment and patient survival.  

http://abstract.rsna.org/uploads/2014/14003782/14003782_pjsa.pdf

Baxi, A, Restrepo, C, Bean, G, Mumbower, A, McCarthy, M, Katre, R, Siddiqui, M, Thoracic Manifestations of Sickle Cell Disease: Complete Radiological Spectrum.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14003782.html