Nasim R. Khadem MD, Presenter: Nothing to Disclose

Daphne Kim Walker MD, Abstract Co-Author: Nothing to Disclose

Review pathophysiology, imaging, treatment, & mimics of gestational trophoblastic neoplasia (GTN) Review incidence, diagnostic criteria, imaging, & treatment of persistent GTN (pGTN) Discuss roles of US, CT, MRI, and PET CT in detection, surveillance, & staging

GTN -Spectrum: hydatiform molar pregnancy (complete/partial), invasive mole, choriocarcinoma, placental site trophoblastic tumor, ectopic mole -Treatment -Mimics (e.g. leiomyomas, Breus mole) pGTN -Diagnostic criteria -Treatment Radiologists' role in diagnosis/management -US, CT, MR, & PET CT for detection, staging, and surveillance -Future directions Select case examples from our institution to include: -Metastatic choriocarcinoma on US/PET CT/MR -Invasive mole status post dilation & curettage, complicated by uterine arteriovenous fistula on US/CT -Mole mimic (degenerative fibroids) on US/CT/MR -Pathologically proven ectopic molar pregnancy on US -pGTN as invasive mole with theca lutein cysts on US/CT Summary GTN/pGTN is commonly encountered in clinical practice. Our goals: 1) Increase awareness of the pathophysiology & management of this disease to help the radiologist to continue to play a major role in diagnosis & surveillance; 2) Review the appropriateness of various imaging modalities in the management of GTN/pGTN.

http://abstract.rsna.org/uploads/2014/14003390/14003390_zneh.pdf

Khadem, N, Walker, D, Gestational Trophoblastic Neoplasia: Spectrum of Disease, Multimodality Imaging, and Management.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14003390.html