Yin Jie Chen MD, Presenter: Nothing to Disclose

Arastoo Vossough MD, PhD, Abstract Co-Author: Nothing to Disclose

Laurie A. Loevner MD, Abstract Co-Author: Nothing to Disclose

Farbod Nasseri MD, Abstract Co-Author: Nothing to Disclose

Suyash Mohan MD, Abstract Co-Author: Nothing to Disclose

1. Review the anatomy of middle cerebellar peduncles (MCP) and associated fiber tracts 2. Discuss how to characterize bilateral MCP lesions in narrowing the differential diagnoses 3. Present an interactive case series on bilateral MCP lesions to improve diagnostic accuracy of radiologists  

1. MCP - anatomy, vascular supply, and associated fiber tracts 2. Interactive case series with relevant clinical data and key differential diagnostic features A. Neurodegenerative - Sporadic olivopontocerebellar atrophy - Parkinson-plus syndromes - Spinocerebellar ataxia - Fragile X-associated tremor/ataxia syndrome B. Metabolic - Adrenoleukodystrophy - Hepatic encephalopathy - Extra-pontine myelinolysis - Hypoglycemia C. Cerebrovascular - Infarction - Posterior reversible encephalopathy syndrome D. Infectious / Inflammatory - Multiple sclerosis - Neurosarcoidosis - PML in HIV - Rhombencephalitis - ADEM E. Neoplastic - Glioma - Lymphoma - Metastasis / meningeal carcinomatosis F. Genetic / Developmental - Pontine tegmental cap dysplasia - Von Hippel-Lindau disease 3. Conclusion - Understanding how underlying pathophysiology relate to certain imaging patterns, combined with relevant clinical data, is very useful in narrowing the differential diagnoses of bilateral MCP abnormalities.

http://abstract.rsna.org/uploads/2014/14003062/14003062_7rcq.pdf

Chen, Y, Vossough, A, Loevner, L, Nasseri, F, Mohan, S, How Do Stalks Wither? – An Interactive Case Series on Bilateral Middle Cerebellar Peduncle Abnormalities.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14003062.html