Anca Ligia Grosu MD, Presenter: Nothing to Disclose

1) Clinical problem: Limitations of the morphological/radiological investigations (CT and MRI) for the detection of the gross tumor mass and visualization of tumor biology. 2) Gross Tumor Volume (GTV) Delineation: Amino- Acids PET (AA-PET) and SPECT: a. Sensitivity and specificity of MET-PET, FET-PET and IMT-SPECT b. Comparison MET-PET, FET-PET and IMT-SPECT c. AA-PET for GTV delineation in gliomas d. Future trials. 3) Tumor Biologys: a. Glucose metabolism: FDG-PET b. Tumor proliferation: FLT-PET c. Tumor hypoxia: F-MISO-PET d. Tumor angiogenesis: RGD-PET, MRI e. Visualization of tumor stemm cells in vivo: animal-PET f. Tumor heterogeneity: MRI.

Grosu, A, Imaging Surrogate Markers in CNS Tumors.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14002110.html