Anne Negard MD, PhD, Presenter: Nothing to Disclose

Kathrine Roe, Abstract Co-Author: Nothing to Disclose

Jorgen Jahnsen MD, PhD, Abstract Co-Author: Nothing to Disclose

Bo Daniel Karlsson MD, Abstract Co-Author: Nothing to Disclose

Stein Harald Holmedal MD, Abstract Co-Author: Nothing to Disclose

Njal Bakka MD, Abstract Co-Author: Nothing to Disclose

Arne Faerden MD, PhD, Abstract Co-Author: Nothing to Disclose

Morten Vatn, Abstract Co-Author: Advisor, Genetic Analysis

Anne Hansen Ree MD, PhD, Abstract Co-Author: Nothing to Disclose

1. To present morphological findings of Crohns disease (CD) and secondary malignancy with conventional Magnetic Resonance Imaging (MRI) and Computer tomography (CT) and to discuss the limitations of these techniques to distinguish inflammation from malignancy of the gastrointestinal (GI) tract 2. To describe novel functional MRI sequences as diffusion-weighted imaging (DWI), spectroscopy, magnetization transfer (MT) and dynamic contrast enhanced imaging (DCE) and to discuss how these techniques can improve the differentiation of inflammation and secondary malignancy in CD.

1. Introduction 2. CT technique  3. MRI technique with morphological sequences 4. CT and MRI findings in CD 5. CT and MRI findings of secondary GI malignancy 6. Novel functional MRI sequences The major teaching points of this exhibition are: 1. MRI and CT findings of CD are increased bowel wall thickness with skip lesions in  between, combs sign and if the patient develops  fistulas, the finding of extraintestinal tubular structures. 2. Secondary malignancy can be suspected if an expansive lesion of the bowel or the fistula develops. 3. Morphological image findings of CD and secondary malignancy overlap and the introduction of novel functional MRI sequences may  improve this differentiation.      

http://abstract.rsna.org/uploads/2014/14001912/14001912_myab.pdf

Negard, A, Roe, K, Jahnsen, J, Karlsson, B, Holmedal, S, Bakka, N, Faerden, A, Vatn, M, Ree, A, Crohn's Disease and Secondary Gastrointestinal Malignancy: Morphological Findings with MRI and CT and How Novel Functional MRI Sequences Can Improve Diagnostics.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14001912.html