C. Carl Jaffe MD, Presenter: Nothing to Disclose

John B. Freymann BS, Presenter: Nothing to Disclose

Justin Kirby, Presenter: Stockholder, Myriad Genetics, Inc

Fred William Prior PhD, Presenter: Research collaboration, Electrical Geodesics, Inc

Lawrence R. Tarbox PhD, Presenter: Nothing to Disclose

1) Understand software methods to extract internet-accessible clinical and image (radiology, pathology and metadata) that power merged data extractions from multiple data sources, and supported by Cloud services and software APIs. 2) Comprehend how the NCI TCIA cancer image archive is linked to the NIH Genome Research Institute's open access genomic database, The Cancer Genome Atlas (“TCGA”) to research disease ‘signatures’ that are essential for ‘precision’ medicine. 3) Attendees will benefit from this workstation-based hands-on tutorial to learn how to conduct their own independent comprehensive disease research on this emerging scientific frontier.

Combined genomic/clinical/pathology data-sets, publically available, are increasingly important to advance disease understanding and treatment. But links to the anatomic-physiologic data that clinical imaging offers has been limited till now by a lack of access to clinically relevant databases/archives that encompass a complete signature of disease. This hands-on session will teach the basic skills for navigating a comprehensive open-access extensive image database (radiology and pathology images) provided in combination by the NIH Cancer Genome Atlas and Cancer Imaging Programs. With this knowledge radiologists and imaging scientists can more readily participate in cutting-edge research by linking imaging to discovery of genomic disease signatures.

http://cancerimagingarchive.net

Jaffe, C, Freymann, J, Kirby, J, Prior, F, Tarbox, L, Radio-Genomic Research: Accessing Clinical Imaging-Genomics-Pathology Data from Public Archives—The Cancer Imaging Archive (Hands-on).  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14001870.html