To understand the new concept of minimally invasive adenocarcinoma of the lung (MIA) proposed by the International Association for the Study Lung Cancer, American Thoracic Society, and European Respiratory Society.
To review and validate the contribution of thin-section CT with special attention to ground-glass opacity (GGO) for small peripheral lung adenocarcinomas associated with good prognosis after surgical resection.
To propose a simple and practical CT criteria for MIA for selecting candidates suitable for limited surgical resection.
Radiologic-pathologic correlation
Atypical Adenomatous Hyperplasia (AAH)
Adenocarcinoma in situ (AIS)
Minimally invasive adenocarcinoma (MIA)
Invasive adenocarcinoma with lepidic growth predominant
Methods of differentiating MIA from invasive adenocarcinoma on CT
Visual assessment of the GGO area using the lung window (>50%)
Maximum diameter of the solid component versus that of the tumor with GGO using the lung window (<0.5)
Semi-quantitative measurement:Tumor disappearance rate using the mediastinal and lung window (>0.5)
Quantitative analysis using computer software: Computer-aided nodule assessment
Kuriyama, K,
Kodama, Y,
Minimally Invasive Adenocarcinoma of the Lung on Thin-section CT. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14001727.html