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The field of molecular MRI has exploded in the last decade, with hundreds of different concepts and probe designs developed and tested in vitro and in vivo. This talk will attempt at giving a structured overview over this vast arsenal of potentially useful approaches by focusing on those that have the highest potential for clinical translation. The approaches will be grouped into 6 major categories and their principles explained and illustrated with key examples: 1) Multimodal nanoparticles; 2) Activatable MRI probes; 3) Targeted superparamagnetic iron oxide nanoparticles; 4) non-targeted superparamagnetic iron oxide nanoparticles; 5) MRI-based Radiogenomics; and 6) Hyperpolarized magnetic resonance spectroscopic imaging.
Kircher, M,
Magnetic Resonance Molecular Imaging. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14001574.html