Christopher Jean-Pierre Francois MD, Presenter: Research support, General Electric Company

1) Describe MRI physics of 4D flow MRI. 2) Illustrate use of 4D flow MRI for basic hemodynamic function. 3) Demonstrate potential futures uses of 4D flow MRI for advanced hemodynamic analyses.

MRI flow imaging is based on flow-sensitive, phase contrast sequences. This presentation will introduce the basic MRI physics responsible for imaging flow, extending 1-directional flow imaging to 3-directional flow imaging used in 4D flow MRI. Examples from valvular and congenital heart disease will be used to illustrate the use of 4D flow MRI to quantify flow velocities and volumes. Although 4D flow MRI is still very much in the early developmental phase, published data comparing 4D flow MRI to established techniques for quantifying flow will be reviewed. The future potential for 4D flow MRI to be used to non-invasively quantify more advanced hemodynamic parameters will be demonstrated. Specifically, the use of 4D flow MRI to measure pressure gradients, pulse wave velocity, wall shear stress and kinetic energy will be covered.  

Francois, C, 4D Flow MRI Quantification?.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/14000908.html