1) Apply CMR for morphometry and quantification of valvular function. 2) Compare various CMR approaches for assessment of cardiac valves. 3) Analyse flow data in stenotic or incompetent valves.
Introduction: Echocardiography remains first line modality for imaging cardiac valves. In specific cases, however, MR provides complementary quantitative data.
Methods: Most relevant sequences for valve imaging are: 1) Black blood, 2) CineSSFP, and 3) VENCine. Black blood images are fast spin echo sequences. CineSSFP are used for quantification of valvular morphology and motion. Temporal resolution is typically 50ms for a segmented breath hold sequence but may be further shortened by means of parallel imaging or non-breath hold sequences. VENCine is an excellent tool for flow volume and velocity quantification. Volumes are relevant to calculate regurgitant fraction of incompetent valves, velocities are used to calculate degree of stenosis relying on modified Bernoulli equation.
Results: Aortic regurgitation is difficult to evaluate with Echocardiography but easily quantified on VENCine with excellent reproducibility. Regurgitant fraction is defined as Volumeantegrade/Volumeretrograde*100 [%]. Aortic stenosis may also be quantified with MR by measuring the opening area on CineSSFP or by measuring peak velocity in the valve on VENCine and calculation with modified Bernoulli equation (ΔP = 4 * Vmax2). Mitral regurgitation may also be quantified by MRI. Echocardiographic quantification relies predominantely on the extent of the regurgitant jet into the left atrium which is not a reliable sign on MRI, since extent of regurgitant jets depend on various sequence parameters such as field strength and echo time. Pulmonary regurgitation can also be quantified with MRI which is relevant in congenital heart disease such as after surgical repair in tetralogy of Fallot. Pulmonary stenosis, Tricuspid stenosis and regurgitation are no routine indications for MRI but are rather evaluated by echocardiography.
Conclusion: Aortic regurgitation is an excellent indication for MRI, it enables accurate and reproducible quantification.
Bremerich, J,
Quantitative Assessment Cardiac Valves on MRI. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/14000905.html