1) Understand the clinical need and biochemical rationale for the use of hyperpolarized [1-13C] pyruvate for prostate cancer imaging. 2) Demonstrate a multi-hyperpolarized probe approach for simultaneously measuring prostate cancer metabolism and tumor micro-environment. 3) Demonstrate the utility of hyperpolarized 13C MR for measuring prostate cancer aggressiveness and response to therapy. 4) Demonstrate the safety, clinical feasibility, sensitivity and resolution, and future availability of clinical hyperpolarized 13C MR.
Kurhanewicz, J,
The Emerging Clinical Role of Hyperpolarized
13C MR in Prostate Cancer Imaging. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/13012739.html