Abstract Archives of the RSNA, 2014
Dominik Fleischmann MD, Presenter: Research support, Siemens AG
1) Review the epidemiology of aortic side-branch dissections, which can occur as a complication of aortic dissection, or as isolated spontaneous dissections of the visceral or renal arteries. 2) Explain the pathophysiology of side branch malperfusion syndromes. 3) Present the key imaging features which distinguish between the two main mechanisms of side branch malperfusion: local obstruction versus inflow obstruction.
Dissections of aortic side branches is a common complication of Type A and Type B acute aortic dissection which substantially increases mortality. It is important to understand the pathophysiology and the two principle mechanisms of side branch malferfusion in aortic dissection: flow obstruction can be due to (A) local abnormalities, such as occlusive dissection flaps, blind ending false lumen with true lumen occlusion ('windsock'), or frank thrombosis. Side-branch malperfusion may also occur due to (B) limited inflow: The classic situation is complete true lumen collapse in the upstream aorta, resulting in underperfusion of all downstream branches supplied by the true lumen. Wile local obstructions are most commonly treated by stent placement into the diseased side branch, inflow-lesions typically require surgical or endovascular repair of the upstream aorta.
Spontaneous dissections of the celiac, mesenteric, or renal arteries are relatively rare events, and typically present with acute abdominal or flank pain. Dissections of side branch arteries can lead to ischemic complications or to freank rupture. Patients presenting with mesenteric or renal artery dissection require a thorough workup to identify genetic disorders (notably Ehlers Danlos IV), inflammatory conditions (vasculitis), and other entities such as fibromuscular dysplasia and segmental arterial mediolysis (SAM).
Fleischmann, D,
Aortic Branch Dissections. Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL.
http://archive.rsna.org/2014/13012008.html