Ricardo Caldeira Cury MD, Presenter: Research Grant, Astellas Group Research Consultant, Astellas Group Research Grant, General Electric Company Research Consultant, General Electric Company Research Consultant, Novartis AG Research Consultant, Heartflow, Inc

1) To review the available evidence supporting the use of Stress CT perfusion. 2) To understand the importance of combining anatomy and physiology in the non-invasive evaluation of chest pain patients. 3) To describe the limitations and understand the future directions of Stress CTP.

A major limitation of coronary CTA is that the physiological significance of stenotic lesions identified is often unknown. Stress myocardial computed tomography perfusion (CTP) is a novel examination that provides both anatomic and physiological information. Multiple single-center studies have established the feasibility of stress myocardial CTP. Furthermore, it has been illustrated that a combined CTA/CTP protocol improves the diagnostic accuracy to detect hemodynamic significant stenosis as compared with CTA alone; this combined protocol can also be accomplished at a radiation dose comparable to nuclear myocardial perfusion imaging exams. Stress CTP is a modality with significant potential, particularly in the evaluation of chest pain patients, given the advantages of short exam time and comprehensive data acquisition. This lecture will summarize the current literature, indications, limitations and discuss future directions of Stress CTP.

Cury, R, Adenosine Stress/Rest CT.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/13010468.html