Binsheng Zhao DSc, Presenter: License agreement, Varian Medical Systems, Inc License agreement, Keosys License agreement, Hinacom Software and Technology, Ltd License agreement, AG Mednet, Inc

1) Demonstrate the feasibility of computer-aided (tumor) volume measurement and explain its potential to improve conventional response assessment in oncology. 2) Familiarize the audience with sources of variation in measuring tumor volume and tumor volume change. 3) Discuss the need for standardizing both imaging and measurement techniques in the interpretation of tumor measurement and thus in response assessment.

Volumetric CT (VolCT) shows potential as a better method to assess tumor response, especially early response, to therapy than the conventional diameter methods. This refresher course will first show how the volumes of solid tumors can be accurately and practically obtained with the help of computer software, then discuss the factors that can affect measurement reproducibility of in vivo tumors during image acquisition and tumor measurement. By becoming acquainted with a well-designed series of (clinical) variability studies, the audience will learn the magnitudes of variability that can occur in the measurement of tumor volumes, as well as in tumor diameter(s).

Zhao, B, Variability in CT Measurement of Tumor Volumes and Its Impact on Response Assessment.  Radiological Society of North America 2014 Scientific Assembly and Annual Meeting, - ,Chicago IL. http://archive.rsna.org/2014/12020958.html