Anabel Medeiros Scaranelo MD, PhD, Abstract Co-Author: Nothing to Disclose

Karina Bukhanov MD, Abstract Co-Author: Nothing to Disclose

Hadas Moshonov PhD, Abstract Co-Author: Nothing to Disclose

Supriya Ravindra Kulkarni MD, DMRD, Abstract Co-Author: Nothing to Disclose

Pavel Crystal MD, Presenter: Nothing to Disclose

To determine differences in the recall rate between Digital Mammography with Breast Tomosynthesis (DBT) and standard 2D-view FFDM (2D) in baseline screening.

REB approved study initiated March 2012 and lasting 362 days, informed consent obtained from all consecutive women scheduled for baseline mammography randomized to 2 clinical sites-teaching hospitals. One site performed DBT (Dimensions, Hologic, Bedford, MA) and the other 2D (Senograph 200D, GE Medical Systems, Milwalkee, Wis). Certified DBT radiologists reported all exams at both sites without the knowledge of the study. Recall rates were calculated for each site and stratified by lesion type, breast density and age. Fisher's exact tests used to determine statistically significant relationships

853 women, (90% screening and 10% diagnostic baseline mammography); n=451 site withDBT; n=402 site with2D. Of 451 women, 37% declined tomosynthesis, where 245 had screeningDBT. The mean age was 44.33 (ranged 26-71) in the group withDBT and 43.51 (ranged 26-79) with2D screening (n=364). The DBT group recall rate was 13.1% compared to 18.7% for 2D (p=0.066) with a trend to statistical significance. Recall rates stratified by lesion type demonstrated significantly lower recall rates for asymmetries (21.9% vs. 60.3%, p=0.0001) but not for calcifications (18.8% vs. 8.8%, p=0.198) when comparing DBT to 2D. There was no significant difference in distribution of breast densities between the two cohorts (p=0.459). Lower recalls in DBT for non-dense breasts showed statistical trend (p=0.0672): fatty breasts (5.5% vs. 23.5%, p=0.1774), scattered densities (12.5% vs. 20.13%, p=0.1568), heterogeneously dense (14.2% vs. 20.2%, p=0.2080), and extremely dense (15% vs. 5%, p=0.3216), (DBT vs 2D, respectively). There was no significant difference in the mean age of patients with or without recall (p=0.591). Lower recall rates using DBT: for women older than 50 years (13.5% vs. 19.6%, p=0.4646) and aged 26-49 years (12.9% vs. 18.4%, p=0.1305) (DBT vs. 2D respectively

A lower recall rate was found in the group of women undergoing DBT and the benefit using this technology for asymmetries was demonstrated

Baseline DBT significantly reduces recall rates for asymmetries. Not receiving recall for additional views reduces women anxiety, less radiation when considered all additional views associated.

Scaranelo, A, Bukhanov, K, Moshonov, H, Kulkarni, S, Crystal, P, Recall Rates on Baseline Screening Mammography: Initial Experience Using Digital Breast Tomosynthesis (DBT).  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13025470.html