Jackson Douglas Hamilton MD, Presenter: Stockholder, Merck KgaA

Jill Vanessa Hunter MD, Abstract Co-Author: Nothing to Disclose

Lakshmi Chavali BS, Abstract Co-Author: Employee, Anatom-e XRT Information Systems, Ltd

Vinodh Ashok Kumar MD, Abstract Co-Author: Nothing to Disclose

Claro Ison MD, Abstract Co-Author: Nothing to Disclose

Sujit Prabhu MD, Abstract Co-Author: Nothing to Disclose

Komal Bankim Shah MD, Abstract Co-Author: Nothing to Disclose

Christiane Matuschek, Abstract Co-Author: Nothing to Disclose

Edwin Boelke, Abstract Co-Author: Nothing to Disclose

Rivka Rachel Colen MD, Abstract Co-Author: Nothing to Disclose

T. Linda Chi MD, Abstract Co-Author: Nothing to Disclose

Dawid Schellingerhout MD, Abstract Co-Author: Nothing to Disclose

Gregory N. Fuller MD, PhD, Abstract Co-Author: Nothing to Disclose

L. Anne Hayman MD, Abstract Co-Author: Founder, Anatom-e XRT Information Systems, Ltd

Ashok J. Kumar MD, Abstract Co-Author: Nothing to Disclose

To describe the common spread pattern behavior of gliomas of the posterior cingulate and retro-cingulate cortex using confocal reconstructions of MR images and Brodmann nomenclature.

Twenty diffuse gliomas cases  involving the posterior cingulate (Brodmann area [BA] 23 & 31) and 5 cases involving the retro-cingulate cortex (BA 26,29,&30) were retrospectively analyzed. The posterior cingulate spread pattern follows the white matter pathways with an often discontinuous, sagittal, “double barrel” pattern. This must be differentiated from primary or secondary involvement of the callosal fibers which can rapidly disseminate tumor to the superomedial frontoparietal lobes coronally. In 3 cases, growth of a callosal tumor will cause herniation through the thin callosal isthmus into the ventricles. Retrosplenial tissues can be reached by the spread from the posterior parahippocampus, optic radiations, or the posterior callosum. Functional and neurosurgical importance will be discussed.

Posterior cingulate gliomas spread via white matter tracts in predictable patterns with clinical ramifications.

Hamilton, J, Hunter, J, Chavali, L, Kumar, V, Ison, C, Prabhu, S, Shah, K, Matuschek, C, Boelke, E, Colen, R, Chi, T, Schellingerhout, D, Fuller, G, Hayman, L, Kumar, A, Predicting the Spread of Glial Tumors: Insights from the Posterior and Retrosplenial Cingulate Cortex (BA 23, 31, 26, 29, & 30).  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13024956.html